Metrabase

Metabolism and Transport Database

Proteins

Download FASTA sequences

Transporters

Protein symbol Gene symbol Name Activity count Compound count UniProt ID HGNC ID
ASBT SLC10A2 solute carrier family 10 (sodium/bile acid cotransporter family) member 2 89 82 Q12908 10906
BCRP1 ABCG2 ATP-binding cassette sub-family G (WHITE) member 2 1,960 980 Q9UNQ0 74
GLUT1 SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 110 83 P11166 11005
LAT1 SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 14 6 Q01650 11063
MCT1 SLC16A1 solute carrier family 16 member 1 (monocarboxylic acid transporter 1) 50 38 P53985 10922
MDR1 ABCB1 ATP-binding cassette sub-family B (MDR/TAP) member 1 2,459 1,182 P08183 40
MRP1 ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 233 194 P33527 51
MRP2 ABCC2 ATP-binding cassette sub-family C (CFTR/MRP) member 2 999 519 Q92887 53
MRP3 ABCC3 ATP-binding cassette sub-family C (CFTR/MRP) member 3 322 133 O15438 54
MRP4 ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4 71 66 O15439 55
OATP1A2 SLCO1A2 solute carrier organic anion transporter family, member 1A2 188 112 P46721 10956
OATP1B1 SLCO1B1 solute carrier organic anion transporter family member 1B1 1,105 444 Q9Y6L6 10959
OATP1B3 SLCO1B3 solute carrier organic anion transporter family member 1B3 629 344 Q9NPD5 10961
OATP2A1 SLCO2A1 solute carrier organic anion transporter family member 2A1 18 16 Q92959 10955
OATP2B1 SLCO2B1 solute carrier organic anion transporter family, member 2B1 758 365 O94956 10962
OATP3A1 SLCO3A1 solute carrier organic anion transporter family member 3A1 21 13 Q9UIG8 10952
OATP4A1 SLCO4A1 solute carrier organic anion transporter family member 4A1 12 9 Q96BD0 10953
OCT1 SLC22A1 solute carrier family 22 (organic cation transporter) member 1 1,057 506 O15245 10963
OSTA SLC51A solute carrier family 51, alpha subunit 0 0 Q86UW1 29955
OSTA/OSTB solute carrier family 51 6 6
OSTB SLC51B solute carrier family 51, beta subunit 0 0 Q86UW2 29956
PEPT1 SLC15A1 solute carrier family 15 (oligopeptide transporter) member 1 1,042 475 P46059 10920


Cytochrome P450s (CYPs)

Protein symbol Gene symbol Name Activity count Compound count UniProt ID HGNC ID
CYP1A1 CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1 15 14 P04798 2595
CYP1A2 CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2 17 16 P05177 2596
CYP1B1 CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1 13 13 Q16678 2597
CYP2C19 CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19 36 29 P33261 2621
CYP2C8 CYP2C8 cytochrome P450, family 2, subfamily C, polypeptide 8 3 3 P10632 2622
CYP2C9 CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9 32 26 P11712 2623
CYP2D6 CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6 71 48 P10635 2625
CYP2E1 CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1 28 27 P05181 2631
CYP2S1 CYP2S1 cytochrome P450, family 2, subfamily S, polypeptide 1 97 56 Q96SQ9 15654
CYP2W1 CYP2W1 cytochrome P450, family 2, subfamily W, polypeptide 1 40 37 Q8TAV3 20243
CYP3A4 CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4 126 98 P08684 2637
CYP3A5 CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5 3 3 P20815 2638
CYP4B1 CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1 25 14 P13584 2644