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Metrabase
Metabolism and Transport Database



Protein list

Download FASTA sequences

Transporters

List of transport proteins
# Protein symbol Gene symbol Name Activity count Compound count UniProt ID HGNC ID
1 MDR1 ABCB1 ATP-binding cassette sub-family B (MDR/TAP) member 1 2460 1182 P08183 40
2 BCRP1 ABCG2 ATP-binding cassette sub-family G (WHITE) member 2 1961 980 Q9UNQ0 74
3 OATP2A1 SLCO2A1 solute carrier organic anion transporter family member 2A1 18 16 Q92959 10955
4 OATP4A1 SLCO4A1 solute carrier organic anion transporter family member 4A1 12 9 Q96BD0 10953
5 MRP2 ABCC2 ATP-binding cassette sub-family C (CFTR/MRP) member 2 1002 520 Q92887 53
6 MCT1 SLC16A1 solute carrier family 16 member 1 (monocarboxylic acid transporter 1) 48 36 P53985 10922
7 OCT1 SLC22A1 solute carrier family 22 (organic cation transporter) member 1 1051 504 O15245 10963
8 MRP3 ABCC3 ATP-binding cassette sub-family C (CFTR/MRP) member 3 323 133 O15438 54
9 PEPT1 SLC15A1 solute carrier family 15 (oligopeptide transporter) member 1 1048 475 P46059 10920
10 ASBT SLC10A2 solute carrier family 10 (sodium/bile acid cotransporter family) member 2 89 82 Q12908 10906
11 OATP3A1 SLCO3A1 solute carrier organic anion transporter family member 3A1 21 13 Q9UIG8 10952
12 OATP1B1 SLCO1B1 solute carrier organic anion transporter family member 1B1 1105 444 Q9Y6L6 10959
13 OATP1B3 SLCO1B3 solute carrier organic anion transporter family member 1B3 630 345 Q9NPD5 10961
14 OSTA SLC51A solute carrier family 51, alpha subunit 0 0 Q86UW1 29955
15 OSTB SLC51B solute carrier family 51, beta subunit 0 0 Q86UW2 29956
16 OSTA/OSTB solute carrier family 51 6 6
17 GLUT1 SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 110 83 P11166 11005
18 MRP4 ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4 73 67 O15439 55
19 OATP1A2 SLCO1A2 solute carrier organic anion transporter family, member 1A2 188 112 P46721 10956
20 OATP2B1 SLCO2B1 solute carrier organic anion transporter family, member 2B1 759 365 O94956 10962
21 LAT1 SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 14 6 Q01650 11063
22 MRP1 ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 236 195 P33527 51

Cytochrome P450s (CYPs)

List of cytochrome P450 enzymes
# Protein symbol Gene symbol Name Activity count Compound count UniProt ID HGNC ID
1 CYP3A4 CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4 127 99 P08684 2637
2 CYP2E1 CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1 28 27 P05181 2631
3 CYP2D6 CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6 71 48 P10635 2625
4 CYP2C9 CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9 32 26 P11712 2623
5 CYP1A2 CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2 17 16 P05177 2596
6 CYP2C19 CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19 36 29 P33261 2621
7 CYP1A1 CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1 15 14 P04798 2595
8 CYP1B1 CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1 13 13 Q16678 2597
9 CYP2S1 CYP2S1 cytochrome P450, family 2, subfamily S, polypeptide 1 97 56 Q96SQ9 15654
10 CYP4B1 CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1 25 14 P13584 2644
11 CYP2W1 CYP2W1 cytochrome P450, family 2, subfamily W, polypeptide 1 40 37 Q8TAV3 20243
12 CYP2C8 CYP2C8 cytochrome P450, family 2, subfamily C, polypeptide 8 3 3 P10632 2622
13 CYP3A5 CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5 4 4 P20815 2638


Department of Chemistry

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